In 303 A.D., Barbara is the beautiful, twenty-year old daughter of Dioscoro, the Roman governor during a time of fierce Christian persecution. Barbara is a pagan, but when Giuliana, a slave raised alongside her almost like a sister, is condemned to death for her Christian faith, Barbara rebels.
She valiantly attempts to save Giuliana, as well as other Christians being persecuted, boldly protesting to her father and other government leaders. When that fails, Barbara makes a daring plan for the successful escape from prison of her Christian friends.
Saint Barbara is also the story of her profound love for Claudio, the noble Roman soldier whose life she saves, as well as her deep compassion for all afflicted humanity. The courageous and holy witness of her Christian friends inspires her to convert to their religion, a decision which will eventually cost Barbara her life.